RAF Typhoon FGR4s have operated alongside French warplanes in a joint strike against an subterranean weapons facility in Syria employed by the IS group, per a report from the British defence ministry.
The facility, located using intelligence, was believed to be storing arms and explosives, the statement said, and was located in hills just north of the historic site of Palmyra in Syria's central region.
"Our fighter planes utilized precision-guided Paveway IV munitions to target a series of approach shafts leading to the depot... preliminary assessments indicate the strike was effective," officials stated.
There was no evidence of any harm to civilians in the operation conducted Saturday night and every plane involved returned to base without incident, the defence officials confirmed.
The Typhoon fighters were assisted by a Voyager tanker plane.
Daesh - alternatively referred to as the so-called Islamic State - enforced jihadist rule over significant areas in Syria and Iraq prior to its 2019 collapse.
"This strike underscores British leadership, and commitment to operate in unison with our partners, to stamp out any resurgence of IS and their dangerous and violent ideologies in the region," the British Defence Secretary John Healey remarked.
RAF aircraft have carried out surveillance missions over Syria to "deter any attempted comeback" of IS subsequent to its defeat at the climactic battle in Baghuz in 2019, the authorities noted.
"I extend gratitude to all the members of the UK armed forces participating in this strike for their professionalism and their bravery," the Defence Secretary commented. "Including them were numerous UK service members on duty over Christmas and New Year. This mission, to take out militants who threaten our safety, highlights how British military are prepared to act, continuously, keeping Britain secure at home and strong abroad."
In December, the American forces conducted what it termed a "massive strike" targeting IS targets in Syria, after an assault claimed the lives of two American soldiers and a civilian linguist in the Palmyra area.
The United Nations reports IS still maintains between 5,000 and 7,000 fighters in Syria and Iraq.